SPRAVATOⓇ: The Complete Guide to Nasal Therapy for Treating Depression

SPRAVATOⓇ, a nasal therapy for depression, has become a promising solution for those battling treatment-resistant depression. Not only has this method shown rapid results in alleviating depressive symptoms, it is also covered by many insurance carriers – making it a game-changer treatment for many.

Key benefits of nasal therapy for depression:

  • FDA Approved: Specifically for treatment-resistant depression.
  • Rapid Relief: Provides quick alleviation of depressive symptoms.
  • Active Ingredient: Esketamine, a powerful derivative of ketamine.

Lately, SPRAVATOⓇ has been turning heads in the medical community, thanks to its ability to rapidly ease depressive symptoms in high-suicide-risk individuals. It’s also becoming a go-to option for those who haven’t found relief with typical oral antidepressants.

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How Does Esketamine Work?

Esketamine is a derivative of ketamine, but it’s more potent and specifically designed to treat depression. Unlike traditional antidepressants that increase serotonin, norepinephrine, and dopamine levels, esketamine works by increasing glutamate levels. Glutamate is the most abundant neurotransmitter in the brain.

By boosting glutamate, esketamine improves communication between brain cells more effectively, leading to rapid symptom relief. This mechanism of action allows esketamine to impact more brain cells at once, providing quicker results than conventional antidepressants.

Esketamine How it works.

Effectiveness and Benefits of Nasal Therapy

Comparing Nasal Therapy to Other Treatments

Nasal therapy for depression, such as with SPRAVATOⓇ (esketamine), has shown significant promise in treating treatment-resistant depression (TRD). Traditional antidepressants, like SSRIs and SNRIs, often take weeks to show effects. In contrast, esketamine can provide rapid symptom relief, sometimes within hours.

Clinical Trials and Response Rates

In clinical trials, patients using esketamine nasal spray experienced response rates of 50% to 70% within the first two weeks. This is considerably higher than the 30% to 40% response rates typically seen with conventional antidepressants. Additionally, remission rates—where symptoms of depression completely disappear—were also higher with esketamine.

Rapid Symptom Relief and Decreased Suicidal Thoughts

One of the most compelling benefits of nasal therapy is its ability to rapidly reduce suicidal thoughts. This makes it a critical option for individuals in crisis. Unlike traditional medications, which can take weeks to reach full effectiveness, esketamine starts working almost immediately.

Brain Health

Esketamine’s unique action on the brain’s glutamate system not only provides quick relief but may also promote brain health. By enhancing communication between brain cells, esketamine helps improve overall brain function, which can lead to better long-term outcomes.

Who is a Good Candidate?

Nasal therapy with esketamine is specifically designed for individuals with major depressive disorder or treatment-resistant depression—those who have not found relief from at least two different antidepressants. However, not everyone is a suitable candidate.

Failed Antidepressants and Exclusion Criteria

If traditional antidepressants haven’t worked for you, and you’re seeking alternatives, esketamine could be an option. However, certain conditions can exclude you from this treatment:

  • Bipolar Disorder: Esketamine is not recommended for depression linked to bipolar disorder.
  • Schizophrenia or Other Psychotic Disorders: Patients with these conditions should avoid esketamine.
  • Substance Abuse: Active substance abuse (drugs or alcohol) is a contraindication.
  • Hypertension: Uncontrolled high blood pressure can be problematic due to esketamine’s potential to raise blood pressure.
SPRAVATOⓇ: The Complete Guide to Nasal Therapy for Treating Depression Doctor

Potential Side Effects and Considerations

While nasal therapy for depression using SPRAVATOⓇ (esketamine) can provide rapid relief, it’s important to be aware of potential side effects and the commitment involved.

Common Side Effects

Some common side effects of nasal esketamine therapy include:

  • Hallucinations: Some patients experience vivid imagery or sensory distortions.
  • Dissociation: A feeling of being detached from reality or oneself.
  • Nausea: Some patients report feeling queasy or experiencing an upset stomach.
  • Drowsiness: A common side effect that can impact daily activities.
  • Increased Blood Pressure: Esketamine can raise blood pressure, so monitoring is essential.
  • Headache: Some individuals may experience mild to moderate headaches.

Safety Measures

To ensure safety during treatment:

  • Doctor Supervision: All treatments are conducted under strict medical supervision in a clinical setting.
  • Monitoring: Vital signs are continuously monitored to manage any adverse reactions.
  • Support Person: Patients must have someone to drive them to and from sessions, as they cannot drive post-treatment.

Ongoing Therapy

Esketamine nasal spray may be part of a lifelong treatment plan for some individuals. The frequency of treatments typically decreases over time. A typical treatment plan might look like this:

  • Week 1-4: Two visits per week for the first four weeks.
  • Week 5-8: One visit per week for the next four weeks.
  • Maintenance Phase: After the initial eight weeks, treatments may vary from once a week to once a month, depending on the patient’s response & provider recommendation.

Integrating Other Treatments

While esketamine offers rapid relief, it’s often used in conjunction with other treatments. Conventional antidepressants, therapy, and lifestyle changes like exercise and diet can improve the effectiveness of nasal therapy. A holistic approach that includes psychotherapy and mindfulness practices can also improve long-term outcomes.

Conclusion

At Anew Therapy Utah, we understand the complexities of treating mental health conditions like treatment-resistant depression and major depressive disorder. Our approach is customized and patient-centric, ensuring that each individual receives a treatment plan custom to their unique needs.

Rapid Symptom Relief

One of the standout benefits of our treatments, including SPRAVATOⓇ (esketamine) nasal therapy, is the rapid relief of symptoms. Unlike traditional antidepressants that can take weeks to show effects, esketamine offers quicker results, making a significant difference in the lives of those suffering from treatment-resistant depression or major depressive disorder.

Holistic Approach

We believe in a holistic approach to mental health. This means we don’t just focus on alleviating symptoms but also on improving overall well-being. Our team of experienced healthcare professionals provides comprehensive care, addressing both the emotional and physical aspects of mental health.

Mental Health Conditions We Treat

Our services extend beyond depression. We also offer treatment for:

  • Anxiety
  • PTSD
  • Chronic Pain
  • OCD
  • Eating Disorders

By offering a range of treatments, including intramuscular (IM) ketamine therapy and SPRAVATOⓇ, we ensure that our patients have access to the most effective options available.

Why Choose Anew Therapy?

Choosing Anew Therapy means opting for a compassionate, safe, and effective treatment plan. We are committed to walking alongside you on your journey to improved mental health, and giving you a calm, welcoming space to pursue healing. 

If you’re ready to explore SPRAVATOⓇ nasal therapy for depression, click here to learn more.

Anew Therapy Utah Clinic

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