If you have Blue Cross Blue Shield and are considering Spravato for treatment-resistant depression, you’re not alone in wondering about coverage. The short answer is that coverage depends on your specific plan, but many people with Blue Cross Blue Shield have their treatment covered.
Here’s what you need to know about Spravato coverage with Blue Cross Blue Shield in Salt Lake City, how the approval process works, and how Anew Therapy can help you understand your options.
Does Blue Cross Blue Shield Cover Spravato in Salt Lake City?
A number of Blue Cross Blue Shield plans do cover Spravato if you meet the medical criteria, but coverage isn’t automatic. It depends on your specific policy, the type of plan you have, and what your plan requires for approval.
It’s important not to assume coverage just because you have Blue Cross Blue Shield. Two people with the same insurance card can have very different benefits and approval steps.
A good place to start is by calling the member services number on your insurance card to ask about Spravato (esketamine) coverage. Your Spravato provider can also help you check your benefits. At Anew Therapy, our team knows how Blue Cross Blue Shield covers Spravato and can help you find out whether your treatment is covered. We help secure coverage so you can focus on feeling better rather than talking to insurance agents and reviewing documents.

Why Spravato Coverage Can Feel Complicated
Spravato is not a standard take-home prescription. It is an FDA-approved nasal spray that must be administered in a certified treatment center, and patients must be monitored for at least two hours after each session. That in-clinic structure is part of the REMS (Risk Evaluation and Mitigation Strategy) program that governs how Spravato is prescribed and administered.
This is why Spravato coverage can feel more complicated than a regular prescription. Insurance might use both your pharmacy and medical benefits, depending on how your plan handles in-office treatments. Prior authorization is often needed, and your diagnosis paperwork needs to be specific. It also matters whether your treatment center is in-network.
It’s not impossible to figure out, but there are more steps than most people expect at first.
What Blue Cross Patients May Need for Spravato Approval
Every plan is a little different, but there are a few things Blue Cross Blue Shield usually looks for when reviewing a Spravato request. Having this paperwork ready can help your application go more smoothly:
- Diagnosis of treatment-resistant depression or another approved indication, such as major depressive disorder with acute suicidal ideation or behavior
- History of previous antidepressant trials – most plans want to see that a patient has tried and not responded to at least two different antidepressants
- Psychiatric or mental health provider documentation supporting the diagnosis and treatment rationale. If you’re treatment is through Anew Therapy, we take care of this.
- Prior authorization approval before treatment begins – Regence BlueCross BlueShield, which serves many Utah patients, states in public policy materials that most contracts require preauthorization approval of Spravato before coverage applies. Anew Therapy handles the prior authorization submission on your behalf.
- Treatment at a certified Spravato treatment center registered under the REMS program. Anew Therapy is a certified REMS provider.
- Ongoing documentation of clinical benefit for continued therapy beyond the initial induction phase We handle this as part of your ongoing care at Anew Therapy.
There’s a lot to keep track of, which is why having an experienced Spravato provider by your side can make a real difference. At Anew Therapy, we handle clinical documentation, prior authorization submissions, and coordination with your insurance directly, so you don’t have to chase paperwork between providers.

Is Regence the Same as Blue Cross Blue Shield in Utah?
If you’re in Utah and your insurance card says Blue Cross Blue Shield, there’s a good chance your plan is administered by Regence BlueCross BlueShield of Utah, which operates as an independent licensee of the Blue Cross and Blue Shield Association.
For most people, Regence and Blue Cross Blue Shield follow the same general rules. But details like clinical criteria and prior authorization can vary depending on whether you have an individual, employer, or marketplace plan.
Questions to Ask Blue Cross Before Starting Spravato
Before your consultation or first session, it helps to ask your insurer these questions:
- Is Spravato covered under my current plan?
- Is prior authorization required, and if so, what criteria need to be met?
- Is Spravato billed under my pharmacy benefit, my medical benefit, or both?
- Is Anew Therapy considered in-network under my plan?
- What will my copay, coinsurance, or deductible responsibility be for each session?
- What clinical documentation is required to support approval?
- Are ongoing maintenance sessions covered after the initial induction phase?
Write down the answers or ask for them in writing if you can. This information will help your provider prepare your prior authorization request.
How Anew Therapy Helps With Spravato and Insurance
Helping you navigate Spravato prior authorization in Utah is part of what we do at Anew Therapy. You don’t have to handle it alone.
As a certified Spravato treatment center serving Salt Lake County, our team can help you check your benefits, gather the paperwork your plan will likely need, and coordinate the prior authorization process with your care. We’ve worked with Blue Cross Blue Shield plans before and know what the approval process usually looks like.
We can’t guarantee your plan will approve Spravato, and we know the process isn’t always quick or easy. But we can help make it less confusing and make sure your clinical documentation is as complete and accurate as possible.
What If Blue Cross Does Not Approve Spravato?
A denial is frustrating, but it is not necessarily the end of the road. At Anew Therapy, we don’t hand you a denial letter and wish you luck. We help you figure out what comes next.
We can appeal the decision on your behalf. When a prior authorization request is denied, we can submit additional clinical documentation and even request a peer-to-peer review between our providers and your insurance company’s medical reviewer. Denials are sometimes overturned on appeal, and having an experienced provider lead that process makes a difference.
We dig into the reason for the denial. Understanding exactly why a request was rejected helps us determine whether updated documentation, a stronger clinical narrative, or a different approach would improve the outcome on resubmission.
We help you explore affordability options. If insurance coverage remains a barrier, there are other paths worth knowing about. Anew Therapy partners with CareCredit, which allows you to spread the cost of treatment over time. The Johnson & Johnson Patient Assistance Program also includes Spravato as an eligible medicine and may provide it at no cost for patients who meet income and eligibility requirements. We can help you understand whether you qualify and what the enrollment process looks like.
We talk through other treatment options. Spravato is one of several evidence-based options for treatment-resistant depression. If it isn’t the right fit financially or clinically, Anew Therapy also offers TMS, IM ketamine therapy, medication management, and therapy. A denial for one treatment doesn’t close the door on getting help.
Ready to Find Out Whether Spravato Is Covered Under Your Plan?
Treatment-resistant depression is hard enough without having to spend weeks trying to decode insurance language by yourself. If you have Blue Cross Blue Shield and are looking for Spravato treatment in Salt Lake City, Anew Therapy can help you understand your benefits, guide you through the approval process, and help you decide whether Spravato or another treatment is the right next step for you.
To check your Spravato coverage and see if you might be a good candidate for treatment, just call or text us at (801) 980-2690.
